Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17889254 | 0.78 | CHRM3 (0.31) | NCF1 | |
| Hydrochloric Acid SCHEMBL23212665 | 0.76 | — | — | |
| SCHEMBL22519229 | 0.76 | L3MBTL1 (0.41) | L3MBTL1CARM1PRMT6ROCK2ROCK1 | |
| SCHEMBL22475301 | 0.76 | ALOX5 (0.34) | NCF1 | |
| SCHEMBL18155993 | 0.76 | L3MBTL1 (0.41) | L3MBTL1CARM1PRMT6ROCK2ROCK1 | |
| SCHEMBL273581 | 0.76 | — | — | |
| SCHEMBL13165399 | 0.76 | SAT1 (0.39) | L3MBTL1 | |
| SCHEMBL6019205 | 0.76 | SAT1 (0.39) | L3MBTL1 | |
| SCHEMBL1268659 | 0.74 | CYP1A2 (0.33) | CARM1PRMT6 | |
| SCHEMBL3425370 | 0.74 | L3MBTL1 (0.40) | L3MBTL1CARM1PRMT6ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961741-B1 | NOVEL COMPOUNDS AS DUAL INHIBITORS OF PHOSPHODIESTERASES AND HISTONE DEACETYLASES | FUND PARA LA INVESTIG MEDICA APLICADA (ES) | 2017-04-05 | — | — | EP | disclosed |