Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL29709419 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL3759531 | 1.00 | — | — | |
| Imidazole SCHEMBL28274251 | 1.00 | — | — | |
| Imidazole SCHEMBL27935235 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL18062502 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL3767595 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL3759526 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL18062503 | 1.00 | — | — | |
| Imidazole SCHEMBL5862201 | 0.97 | — | — | |
| Imidazole SCHEMBL21632450 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010205-A | Composite treating agent for domestic sewage and preparation method thereof | 浙江上鑫生态科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12496575-B2 | Catalyst composition for cyclic carbonate production from CO2 and epoxides | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2025-12-16 | — | — | US | claimed |
| CN-115873191-B | Pentafluorophenyl aromatic polymer with side chain containing sulfhydryl nitrogen heterocycle, preparation method and application thereof, and preparation method of high-temperature proton exchange membrane | 吉林大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119570482-A | Bi3+、Yb3+Co-doped Cs2ZrCl6Double perovskite microcrystal and preparation method of light conversion film thereof | 北京工业大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119504596-A | Preparation method and application of functional lithium battery anode AT9 coating additive material | 安徽得壹能源科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119499989-A | Reaction heat integration device and method for preparing cyclic carbonate through micro-channels | 中国科学院过程工程研究所 | 2025-02-25 | — | — | CN | claimed |
| CN-119386635-A | Method and device for removing carbon dioxide in boron trifluoride-11 and adsorbent regeneration method | 昊华气体有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-116444711-B | Double-function heterogeneous catalyst and preparation method and application thereof | 浙江理工大学嵊州创新研究院有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119345077-A | Skin care composition with effects of relieving, repairing, moisturizing and relieving itching | 广东康诺达医疗科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119307009-A | Supermolecule ionic polymer exfoliated nano montmorillonite and preparation method thereof | 宁波瑞成包装材料有限公司 | 2025-01-14 | — | — | CN | claimed |
| WO-2005075481-A1 | NOVEL NAPHTHALENE DERIVATIVES AND COLORING AGENTS CONTAINING THESE COMPOUNDS, FOR KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | claimed |
| US-6706710-B2 | SEROTONIN H5-HT1B- RECEPTOR ANTAGONIST, FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS SUCH AS DEPRESSION, ANXIETY, ETC. | ASTRAZENECA AB (SE) | 2004-03-16 | — | — | US | claimed |
| CN-1443178-A | (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphtyl] -4-morpholibenzamide | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | CN | claimed |
| US-20030166653-A1 | Novel form of (r)-n-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide | ASTRAZENECA AB (SE) | 2003-09-04 | — | — | US | claimed |
| EP-1305303-A1 | NOVEL FORM OF (R)- i N /i - 5-METHYL-8-(4-METHYLPIPERAZIN-1-YL)-1,2,3,4-TETRAHYDRO-2-NAPHTHYL]-4-MORPHOLINOBENZAMIDE | AstraZeneca AB (SE) | 2003-05-02 | — | — | EP | claimed |
| WO-2002008212-A1 | NOVEL FORM OF (R)-N-[5-METHYL-8-(4-METHYLPIPERAZIN-1-YL)-1,2,3,4-TETRAHYDRO-2-NAPHTHYL]-4-MORPHOLINOBENZAMIDE | ASTRAZENECA AB (SE) | 2002-01-31 | — | — | WO | claimed |
| EP-0384195-B1 | Reagent for coulometrically determining water capacity | RIEDEL DE HAEN AG (DE) | 1997-08-20 | — | — | EP | claimed |
| US-5139955-A | Reactive base, sulfur dioxide, iodide, conducting salt dissolved in alcoholic solvent; membrane-free cell | RIEDEL-DE HAEN AG (DE) | 1992-08-18 | — | — | US | claimed |
| EP-0182533-B1 | 3-(2-ARYL-2-OXOETHYL)-IMIDAZOLIUM SALTS AS HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1989-09-20 | — | — | EP | claimed |
| CN-87103528-A | 1, the 3-3-disubstituted imidazolium salts | — | 1987-12-02 | — | — | CN | claimed |