Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL29709419 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL28274251 | 1.00 | — | — | |
| Imidazole SCHEMBL27935235 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL18062502 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL3767595 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL3759526 | 1.00 | ALDH1A1 (0.93) | — | |
| Imidazole SCHEMBL187162 | 1.00 | — | — | |
| Imidazole SCHEMBL18062503 | 1.00 | — | — | |
| Imidazole SCHEMBL5862201 | 0.97 | — | — | |
| Imidazole SCHEMBL21632450 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8460581-B2 | Imidazole derivatives and their use of dopants for doping organic semiconductor matrix material | NOVALED AG (DE) | 2013-06-11 | — | — | US | disclosed |
| US-20100301277-A1 | Imidazole Derivatives and Their use as Dopants for Doping an Organic Semiconductor Matrix Material | NOVALED AG (DE) | 2010-12-02 | — | — | US | disclosed |