Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.38 |
| ▸ | USP14 | P54578 | 3/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558014 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CACNA1HUSP14BDKRB2CHRM2 | |
| SCHEMBL27274008 | 0.93 | CACNA1H (0.41) | ALDH1A1CACNA1HUSP14BDKRB2CHRM2 | |
| SCHEMBL20725544 | 0.77 | CHRM2 (0.33) | ALDH1A1USP14CHRM2CHRM4CHRM1 | |
| SCHEMBL13248904 | 0.77 | RECQL (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16543717 | 0.77 | RECQL (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7458942 | 0.77 | ALDH1A1 (0.37) | ALDH1A1USP14CHRM2CHRM4CHRM1 | |
| SCHEMBL18716714 | 0.77 | CACNA1H (0.45) | ALDH1A1CACNA1HMEN1KMT2A | |
| SCHEMBL31271164 | 0.74 | USP14 (0.33) | ALDH1A1USP14CHRM2CHRM4CHRM1 | |
| SCHEMBL20725591 | 0.74 | CACNA1H (0.43) | ALDH1A1CACNA1H | |
| SCHEMBL1268069 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150598-B1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD (JP) | 2019-02-13 | — | — | EP | disclosed |
| EP-3150598-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA Eiyo Ltd. (JP) | 2017-04-05 | — | — | EP | disclosed |