SCHEMBL18717068

CC(=O)N[C@H]1CCC(=O)NCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.54

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	TSLP	Q969D9	11/20	0.54

▸	MC4R	P32245	6/20	0.52

▸	MC3R	P41968	6/20	0.50

▸	MC5R	P33032	3/20	0.49

▸	MC1R	Q01726	2/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7863228	0.94	TSLP (0.59)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL18716881	0.94	TSLP (0.59)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL10089221	0.94	TSLP (0.59)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL18717069	0.94	TSLP (0.59)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL18716869	0.92	MC4R (0.59)	MC4RMC3RMC5RMC1R
SCHEMBL18716878	0.92	MC4R (0.58)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL20642744	0.92	MC4R (0.50)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL16340576	0.91	TSLP (0.57)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL16340610	0.90	TSLP (0.56)	TSLPMC4RMC3RMC5RMC1R
SCHEMBL16340714	0.89	TSLP (0.57)	TSLPMC4RMC3RMC5RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2440572-B1	LACTAM-BRIDGED MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES	PALATIN TECHNOLOGIES INC (US)	2017-04-05	—	—	EP	disclosed