SCHEMBL18717907

SCHEMBL18717907

c1ccc(-n2c3ccccc3c3cc(-c4ccccc4-c4ccccc4-c4ccccc4-c4ccc5c(c4)c4ccccc4n5-c4ccc5ccccc5c4)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PTGER4 P35408 1/20 0.36
HDAC4 P56524 2/20 0.36
HPGD P15428 1/20 0.35
GSTP1 P09211 1/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18717909 1.00 KDM4E (0.49) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL18717901 1.00 KDM4E (0.49) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL18717897 0.99 KDM4E (0.50) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL18717920 0.96 KDM4E (0.41) KDM4EATML3MBTL1HDAC4HPGD
SCHEMBL18717911 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL18717899 0.95 KDM4E (0.46) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL18717903 0.94 L3MBTL1 (0.45) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL17562215 0.93 KDM4E (0.50) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL22876230 0.92 KDM4E (0.45) KDM4EATML3MBTL1PTGER4HDAC4
SCHEMBL23264319 0.92 KDM4E (0.55) KDM4EATML3MBTL1PTGER4HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10522766-B2 Organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-31 US disclosed
US-20170213985-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-07-27 US disclosed
US-20170213985-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-07-27 US disclosed
US-20170104163-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-13 US disclosed
US-20170104163-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170213985-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OCIAD1, ALDH1A2 KDM4E 4146/4885ATM 2865/4885L3MBTL1 4262/4885
US-20170104163-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 KDM4E 4387/4885ATM 4229/4885L3MBTL1 4147/4885
US-10522766-B2 Organic optoelectronic device and display device OCIAD2, OCIAD1, ALDH1A2 KDM4E 4146/4885ATM 2865/4885L3MBTL1 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.