SCHEMBL18718697

SCHEMBL18718697

CCCCCC1CCC(c2ccc(-c3ccc(OCCC)c(F)c3F)c(F)c2)CO1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 10/20 0.35
ALOX5 P09917 1/20 0.33
PDE4A P27815 3/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM1A O60341 2/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
HTR2C P28335 2/20 0.30
HTR2B P41595 2/20 0.30
HTR2A P28223 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18718707 0.99 FPR2 (0.34) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL18718705 0.99 FPR2 (0.34) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL18718700 0.97 FPR2 (0.33) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL18718681 0.97 ALOX5 (0.33) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL18718675 0.97 FPR2 (0.35) FPR2ALOX5PDE4AKDM1APDE4B
SCHEMBL18718682 0.95 FPR2 (0.33) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL18718679 0.94 KDM1A (0.37) FPR2ALOX5SLC6A2SLC6A4SLC6A3
SCHEMBL18718664 0.94 ALOX5 (0.34) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL8943840 0.94 FPR2 (0.37) FPR2ALOX5PDE4ASLC6A2SLC6A4
SCHEMBL18718693 0.93 KDM1A (0.36) FPR2ALOX5SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9909064-B2 Compound having tetrahydropyran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-03-06 US disclosed
US-9909064-B2 Compound having tetrahydropyran ring, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-03-06 US disclosed
US-20170101582-A1 COMPOUND HAVING TETRAHYDROPYRAN RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-04-13 US disclosed
US-20170101582-A1 COMPOUND HAVING TETRAHYDROPYRAN RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-04-13 US disclosed