Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.40 |
| ▸ | ALPL | P05186 | 5/20 | 0.40 |
| ▸ | XIAP | P98170 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272665 | 0.87 | TSHR (0.41) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL13732897 | 0.84 | THRB (0.41) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL13898472 | 0.77 | TSHR (0.48) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL13898659 | 0.75 | TSHR (0.47) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL3810000 | 0.72 | ASAH1 (0.60) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL273285 | 0.71 | TSHR (0.41) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL17853352 | 0.71 | TSHR (0.53) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL19483230 | 0.71 | TSHR (0.50) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL4853630 | 0.70 | TSHR (0.46) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 | |
| SCHEMBL24218338 | 0.69 | ASAH1 (0.43) | TSHRALDH1A1L3MBTL1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101497-A1 | PROTEIN ADHESION INHIBITOR | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-04-13 | — | — | US | disclosed |