Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 8/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12254110 | 0.89 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL15043581 | 0.82 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL25602520 | 0.81 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL9370824 | 0.80 | KDM1A (0.50) | ALDH1A1HPGD | |
| SCHEMBL15046517 | 0.79 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL30444986 | 0.78 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL20168754 | 0.78 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNB4 | |
| SCHEMBL9731015 | 0.75 | GRIA2 (0.40) | MEN1KMT2A | |
| SCHEMBL9365099 | 0.75 | GRIA2 (0.40) | MEN1KMT2A | |
| SCHEMBL9366313 | 0.73 | KDM1A (0.48) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |