Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1872269

Fc1cc(CNC2Cc3ccccc3C2)ccc1Oc1ccc2[nH]cnc2c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.41
HTR5A P47898 1/20 0.36
KDM1A O60341 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
PRMT5 O14744 1/20 0.34
GHSR Q92847 1/20 0.34
HDAC1 Q13547 1/20 0.33
P2RX7 Q99572 1/20 0.33
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
FYN P06241 1/20 0.32
GRIN2B Q13224 1/20 0.32
IL6 P05231 1/20 0.32
TLR7 Q9NYK1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL1878258 0.94 SLC2A1 (0.36) SLC2A1KDM1AMAOAMAOBP2RX7
Trifluoroacetic Acid SCHEMBL1874615 0.91 SLC2A1 (0.38) SLC2A1HTR5APRMT5HDAC1
Trifluoroacetic Acid SCHEMBL1875567 0.91 SLC2A1 (0.38) SLC2A1HTR5APRMT5HDAC1
Trifluoroacetic Acid SCHEMBL1872774 0.91 SLC2A1 (0.40) SLC2A1HTR5APRMT5CARM1PRMT6
Trifluoroacetic Acid SCHEMBL1877883 0.90 SLC2A1 (0.44) SLC2A1HTR5A
Trifluoroacetic Acid SCHEMBL1874603 0.90 SLC2A1 (0.42) SLC2A1HTR5APRMT5HDAC1FYN
Trifluoroacetic Acid SCHEMBL1875560 0.88 SLC2A1 (0.40) SLC2A1HTR5APRMT5HDAC1FYN
Trifluoroacetic Acid SCHEMBL1875501 0.85 CACNA1B (0.37) SLC2A1HTR5AFYN
Trifluoroacetic Acid SCHEMBL1877301 0.85 GHSR (0.37) SLC2A1KDM1AMAOAMAOBGHSR
SCHEMBL12634118 0.85 QPCT (0.39) KDM1AMAOAMAOBGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7939528-B2 Heterocycle compounds GLAXOSMITHKLINE LLC (US) 2011-05-10 US disclosed