Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 4/20 | 0.33 |
| ▸ | QPCT | Q16769 | 3/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | IL6 | P05231 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1872269 | 0.94 | SLC2A1 (0.41) | SLC2A1IL6TLR7P2RX7KDM1A | |
| Trifluoroacetic Acid SCHEMBL1875501 | 0.91 | CACNA1B (0.37) | SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL1877301 | 0.86 | GHSR (0.37) | SLC2A1BRAFQPCTIL6TLR7 | |
| Trifluoroacetic Acid SCHEMBL1875567 | 0.85 | SLC2A1 (0.38) | SLC2A1QPCT | |
| Trifluoroacetic Acid SCHEMBL1872774 | 0.85 | SLC2A1 (0.40) | SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL1874615 | 0.85 | SLC2A1 (0.38) | SLC2A1QPCT | |
| SCHEMBL12634119 | 0.85 | QPCT (0.42) | QPCTIL6TLR7KDM1AMAOA | |
| Trifluoroacetic Acid SCHEMBL1877883 | 0.85 | SLC2A1 (0.44) | SLC2A1QPCT | |
| Trifluoroacetic Acid SCHEMBL1875942 | 0.84 | OPRM1 (0.39) | SLC2A1QPCTKDM1AMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL1879953 | 0.84 | OPRM1 (0.39) | SLC2A1QPCTKDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |