Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16137688 | 1.00 | KMT2A (0.40) | KMT2AMEN1NR1H4MAOBBRD4 | |
| SCHEMBL16114823 | 0.89 | MRGPRX4 (0.40) | KMT2AMEN1NR1H4MAOBBRD4 | |
| SCHEMBL16114824 | 0.89 | MRGPRX4 (0.40) | KMT2AMEN1NR1H4MAOBBRD4 | |
| SCHEMBL16137689 | 0.83 | KMT2A (0.47) | KMT2AMEN1MAOBBRD4PTGER1 | |
| SCHEMBL16137781 | 0.78 | BRD4 (0.38) | KMT2AMEN1NR1H4MAOBBRD4 | |
| SCHEMBL18725150 | 0.76 | MAOB (0.37) | KMT2AMEN1NR1H4MAOBBRD4 | |
| SCHEMBL18725149 | 0.76 | MAOB (0.37) | KMT2AMEN1NR1H4MAOBBRD4 | |
| SCHEMBL11175805 | 0.72 | MEN1 (0.57) | KMT2AMEN1NR1H4MAOBLMNA | |
| SCHEMBL11175800 | 0.72 | MEN1 (0.57) | KMT2AMEN1NR1H4MAOBLMNA | |
| SCHEMBL16115770 | 0.71 | MRGPRX4 (0.47) | KMT2AMEN1MAOBBRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |