Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.41 |
| ▸ | DRD2 | P14416 | 8/20 | 0.41 |
| ▸ | DRD4 | P21917 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 6/20 | 0.40 |
| ▸ | DRD5 | P21918 | 6/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015151 | 0.77 | DRD3 (0.45) | DRD3DRD2 | |
| SCHEMBL27450334 | 0.73 | CA12 (0.48) | DRD3DRD2 | |
| SCHEMBL22296372 | 0.71 | SLC6A2 (0.50) | — | |
| SCHEMBL17302962 | 0.67 | DRD2 (0.43) | DRD3DRD2 | |
| SCHEMBL1608042 | 0.67 | DRD2 (0.59) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL29427014 | 0.67 | DRD2 (0.59) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL1661863 | 0.64 | HDAC4 (0.61) | DRD3DRD2DRD4SIGMAR1NFKB1 | |
| SCHEMBL1658753 | 0.64 | HDAC4 (0.56) | DRD3DRD2DRD4SIGMAR1NFKB1 | |
| SCHEMBL23123632 | 0.63 | DRD3 (0.58) | DRD3DRD2DRD4HTR1ADRD1 | |
| SCHEMBL29786277 | 0.63 | DRD3 (0.58) | DRD3DRD2DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153499-A1 | METHOD FOR PRODUCING N-SUBSTITUTED CARBAMIC ACID ESTER | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2017-04-12 | — | — | EP | disclosed |