Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450334 | 0.83 | CA12 (0.48) | DRD3DRD2CA12ALDH1A1CA2 | |
| SCHEMBL18726697 | 0.77 | DRD3 (0.41) | DRD3DRD2 | |
| SCHEMBL15810322 | 0.73 | KDM4E (0.41) | DRD3DRD2ALDH1A1LMNACYP3A4 | |
| SCHEMBL21358187 | 0.73 | CA12 (0.42) | DRD3DRD2CA12ALDH1A1CA2 | |
| SCHEMBL28015659 | 0.73 | ESR2 (0.41) | CA12ALDH1A1CA2LMNACYP3A4 | |
| SCHEMBL10062055 | 0.72 | DRD3 (0.59) | DRD3DRD2CA12ALDH1A1CA2 | |
| SCHEMBL28085027 | 0.72 | HDAC4 (0.41) | DRD3LMNACYP3A4HSD17B10HTR2C | |
| SCHEMBL29427014 | 0.71 | DRD2 (0.59) | DRD3DRD2CA12ALDH1A1CA2 | |
| SCHEMBL1608042 | 0.71 | DRD2 (0.59) | DRD3DRD2CA12ALDH1A1CA2 | |
| SCHEMBL1661863 | 0.68 | HDAC4 (0.61) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |