Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.43 |
| ▸ | TUBB | P07437 | 4/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23776494 | 0.91 | TUBB4A (0.53) | ALDH1A1SMN1; SMN2L3MBTL1SCN10AKCNH2 | |
| SCHEMBL12231816 | 0.87 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2L3MBTL1SCN10AKCNH2 | |
| SCHEMBL20863743 | 0.79 | TUBB4A (0.41) | ALDH1A1SMN1; SMN2L3MBTL1S1PR4S1PR1 | |
| SCHEMBL14756346 | 0.78 | TUBB4A (0.45) | ALDH1A1S1PR4S1PR1S1PR5TUBB4A | |
| SCHEMBL10707113 | 0.78 | TUBB4A (0.45) | ALDH1A1S1PR4S1PR1S1PR5TUBB4A | |
| SCHEMBL5924403 | 0.78 | BACE1 (0.53) | ALDH1A1S1PR4S1PR1S1PR5TUBB4A | |
| SCHEMBL22487867 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1SCN10AKCNH2 | |
| SCHEMBL18922591 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1SCN10AKCNH2 | |
| SCHEMBL15156602 | 0.76 | SCN10A (0.49) | SCN10AKCNH2S1PR4S1PR1S1PR5 | |
| SCHEMBL846652 | 0.75 | SCN10A (0.78) | ALDH1A1SMN1; SMN2L3MBTL1SCN10AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153515-A1 | COMPOUNDS FOR INHIBITING HEPATITIS C VIRUS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AB Pharma Ltd (CN) | 2017-04-12 | — | — | EP | disclosed |