Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691828 | 0.93 | ALDH1A1 (0.59) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18807111 | 0.89 | STAT3 (0.58) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18807113 | 0.89 | STAT3 (0.57) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29448087 | 0.88 | STAT3 (0.48) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18691815 | 0.88 | STAT3 (0.48) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345519 | 0.88 | STAT3 (0.53) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18730823 | 0.87 | STAT3 (0.56) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18691819 | 0.87 | STAT3 (0.52) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18731231 | 0.87 | STAT3 (0.52) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL17345436 | 0.86 | STAT3 (0.51) | STAT3ALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153508-A1 | NOVEL ANTICANCER AGENT | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2017-04-12 | — | — | EP | disclosed |