SCHEMBL18732016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18731703	0.96	AHR (0.54)	AHRPDK2PGRKDM4EMEN1
	SCHEMBL18732019	0.95	AHR (0.53)	AHRPDK2PGRKDM4EMEN1
	SCHEMBL18731704	0.91	AHR (0.54)	AHRPDK2PGRKDM4EMEN1
	SCHEMBL22930604	0.90	AHR (0.50)	AHRPGRKDM4EMEN1ALDH1A1
	SCHEMBL22617684	0.89	AHR (0.54)	AHRPDK2KDM4EMEN1ALDH1A1
	SCHEMBL16491652	0.89	AHR (0.51)	AHRPGRKDM4EMEN1ALDH1A1
	SCHEMBL18731701	0.86	AHR (0.51)	AHRPGRKDM4EMEN1ALDH1A1
	SCHEMBL24401432	0.85	AHR (0.47)	AHRKDM4EMEN1ALDH1A1MAPT
	SCHEMBL18732008	0.85	AHR (0.50)	AHRPDK2PGRKDM4EMEN1
	SCHEMBL16491690	0.84	AHR (0.53)	AHRPGRKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.