Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19287945 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL19570833 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL19286498 | 0.83 | MEN1 (0.53) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL24758820 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL19574739 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL14325929 | 0.67 | KMT2A (0.60) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL394375 | 0.65 | MEN1 (0.73) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL14303303 | 0.64 | KMT2A (0.57) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL14303304 | 0.62 | KMT2A (0.60) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL903151 | 0.62 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017062862-A2 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2017-04-13 | — | — | WO | disclosed |