Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735172 | 0.90 | MGAM (0.33) | MGAMGAASIMGAM2 | |
| SCHEMBL18735154 | 0.90 | CNR2 (0.31) | — | |
| SCHEMBL18734958 | 0.88 | MGAM (0.33) | MGAMGAASIMGAM2 | |
| SCHEMBL18734929 | 0.88 | METAP2 (0.30) | — | |
| SCHEMBL18735182 | 0.87 | LMNA (0.32) | — | |
| SCHEMBL18735191 | 0.87 | GAA (0.35) | MGAMGAASIMGAM2POLB | |
| SCHEMBL18735051 | 0.85 | MGAM (0.40) | MGAMGAASIMGAM2POLB | |
| SCHEMBL18734933 | 0.82 | — | — | |
| SCHEMBL18734947 | 0.80 | — | — | |
| SCHEMBL18735192 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |