Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 8/20 | 0.32 |
| ▸ | METAP1 | P53582 | 6/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735319 | 0.93 | KMT2A (0.31) | KMT2APOLBMETAP2METAP1L3MBTL1 | |
| SCHEMBL18735327 | 0.91 | ACACB (0.30) | KMT2APOLB | |
| SCHEMBL18735334 | 0.86 | METAP2 (0.34) | METAP2METAP1FAAH | |
| SCHEMBL18735073 | 0.86 | GAA (0.40) | KMT2APOLBL3MBTL1MAPTCYP2C9 | |
| SCHEMBL18735077 | 0.84 | KMT2A (0.35) | KMT2APOLBL3MBTL1CYP2C9CYP3A4 | |
| SCHEMBL18735321 | 0.84 | METAP2 (0.33) | METAP2METAP1 | |
| SCHEMBL18735066 | 0.82 | KMT2A (0.34) | KMT2APOLBL3MBTL1MAPTLMNA | |
| SCHEMBL18735333 | 0.80 | METAP2 (0.33) | METAP2METAP1 | |
| SCHEMBL18735343 | 0.78 | L3MBTL1 (0.39) | KMT2APOLBMETAP2METAP1L3MBTL1 | |
| SCHEMBL18735328 | 0.77 | METAP2 (0.32) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |