Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735329 | 0.89 | L3MBTL1 (0.40) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18734968 | 0.85 | L3MBTL1 (0.36) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735063 | 0.85 | KMT2A (0.50) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735361 | 0.82 | CYP1A2 (0.40) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735061 | 0.78 | KMT2A (0.46) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL5020136 | 0.78 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735349 | 0.78 | CYP1A2 (0.38) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735325 | 0.77 | KMT2A (0.41) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735350 | 0.76 | KMT2A (0.40) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 | |
| SCHEMBL18735343 | 0.76 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |