Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976543 | 1.00 | — | — | |
| SCHEMBL4342558 | 0.97 | — | — | |
| SCHEMBL24904293 | 0.90 | — | — | |
| SCHEMBL24073037 | 0.83 | — | — | |
| SCHEMBL19509515 | 0.77 | L3MBTL3 (0.58) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23153412 | 0.75 | MEN1 (0.56) | HPGDTP53SMN1; SMN2MMP1MMP3 | |
| SCHEMBL3947407 | 0.73 | ALDH1A1 (0.93) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL2323473 | 0.73 | ALDH1A1 (0.93) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL3458615 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL8024247 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209296-B1 | ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2019-07-10 | — | — | EP | claimed |
| US-10072025-B2 | Ethyl N-boc piperidinyl pyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-09-11 | — | — | US | claimed |
| EP-3209296-A1 | ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-08-30 | — | — | EP | claimed |
| US-20170240567-A1 | ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-08-24 | — | — | US | claimed |
| US-7934888-B2 | Marine anti-foulant system and methods for using same | VIV SUPPRESSION, INC. (US) | 2011-05-03 | — | — | US | claimed |
| US-7901701-B2 | Methods for producing dried pesticide compositions | LIGNOTECH USA, INC. (US) | 2011-03-08 | — | — | US | claimed |
| WO-2010127142-A2 | USE OF LIGNOSULFONATES IN SUSPO-EMULSIONS FOR PRODUCING PESTICIDE COMPOSITIONS | LIGNOTECH USA, INC. (US) | 2010-11-04 | — | — | WO | claimed |
| US-20100278890-A1 | Use of Lignosulfonates in Suspo-emulsions for Producing Pesticide Compositions | LIGNOTECH USA, INC. (US) | 2010-11-04 | — | — | US | claimed |
| EP-2244569-A2 | METHODS FOR PRODUCING PESTICIDE COMPOSITIONS | Lignotech Usa, Inc. (US) | 2010-11-03 | — | — | EP | claimed |
| US-20090185867-A1 | MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME | ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL | 2009-07-23 | — | — | US | claimed |
| EP-0052856-A2 | Aryl sulfonylurea carbamates and thiolcarbamates and salts thereof: herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-06-02 | — | — | EP | claimed |
| US-4276078-A | HALOGENATED AMIDE ANTIDOTES FOR THIOCARBAMYL HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1981-06-30 | — | — | US | claimed |
| US-4269618-A | COMPRISING A THIOLCARBAMATE AND AN ANTIDOTE OF A HALOALKYLAMIDO COMPOUND; COATING CROP SEEDS; APPLYING TO THE SOIL | STAUFFER CHEMICAL COMPANY (US) | 1981-05-26 | — | — | US | claimed |
| US-4223070-A | COATING FIRST WITH A LIQUID AND A POLYISOCYANATE THEN AN AQUEOUS SOLUTION OF A POLYMERIZATION CATALYST | STAUFFER CHEMICAL COMPANY (US) | 1980-09-16 | — | — | US | claimed |
| EP-0005302-A2 | Impregnated porous granules with slow-release pore membranes, and process for the manufacture thereof | STAUFFER CHEMICAL COMPANY (US) | 1979-11-14 | — | — | EP | claimed |
| US-4137070-A | CONTAINING HERBICIDAL ANTIDOTE | STAUFFER CHEMICAL COMPANY (US) | 1979-01-30 | — | — | US | claimed |
| US-4042371-A | Sulfide herbicide antidote compositions and method of use | STAUFFER CHEMICAL COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-4036628-A | THIOCARBAMATES, PHOSPHATES, PHOSPHONATES | STAUFFER CHEMICAL COMPANY (US) | 1977-07-19 | — | — | US | claimed |
| US-4033750-A | Herbicidal composition | NIPPON SODA COMPANY LIMITED (JA) | 1977-07-05 | — | — | US | claimed |
| US-4021224-A | THIOCARBAMATE, WEED PEST CONTROL, ANTIDOTES | STAUFFER CHEMICAL COMPANY (US) | 1977-05-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240567-A1 | ETHYL N-BOC PIPERIDINYL PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | JAK1, JAK2, JAK3 | ALDH1A1 2779/4885HPGD 853/4885MAPT 4153/4885 |
| US-10072025-B2 | Ethyl N-boc piperidinyl pyrazolo pyridones as Janus kinase inhibitors | JAK1, JAK2, JAK3 | ALDH1A1 2779/4885HPGD 853/4885MAPT 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.