Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24766470 | 0.81 | ATM (0.41) | POLBCYP2C9ATMMEN1KMT2A | |
| SCHEMBL29155508 | 0.79 | POLB (0.43) | POLBCASP6CYP2C9ATMMEN1 | |
| SCHEMBL15258541 | 0.79 | ALDH1A1 (0.47) | EDNRA | |
| SCHEMBL4948273 | 0.78 | EDNRA (0.44) | POLBCASP6CYP2C9ATMKMT2A | |
| SCHEMBL27219661 | 0.77 | POLB (0.39) | POLBCASP6CYP2C9ATMMEN1 | |
| SCHEMBL8427998 | 0.77 | KMT2A (0.41) | POLBCASP6MEN1USP2KMT2A | |
| SCHEMBL7422948 | 0.77 | KMT2A (0.41) | POLBCASP6MEN1USP2KMT2A | |
| SCHEMBL22835286 | 0.76 | AKR1B1 (0.43) | POLBCASP6AKR1B1 | |
| SCHEMBL24193356 | 0.74 | ABCB1 (0.40) | POLBCASP6CYP2C9ATMMEN1 | |
| SCHEMBL22992510 | 0.74 | ABCB1 (0.39) | POLBCYP2C9ATMAKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066562-A2 | ARTIFICIAL METALLOENZYMES CONTAINING NOBLE METAL-PORPHYRINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-20 | — | — | WO | disclosed |