SCHEMBL29155508

SCHEMBL29155508

O=C(O)C1Oc2ccccc2C1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
CASP6 P55212 1/20 0.43
CYP2C9 P11712 1/20 0.40
ATM Q13315 1/20 0.39
ABCB1 P08183 2/20 0.39
EDNRA P25101 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
GUSB P08236 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24193356 0.79 ABCB1 (0.40) POLBCASP6CYP2C9ATMABCB1
SCHEMBL18740908 0.79 POLB (0.42) POLBCASP6CYP2C9ATMEDNRA
SCHEMBL4948273 0.79 EDNRA (0.44) POLBCASP6CYP2C9ATMEDNRA
SCHEMBL10974720 0.79 POLB (0.47) POLBCASP6CYP2C9LMNAPTGS2
SCHEMBL10974722 0.79 POLB (0.47) POLBCASP6CYP2C9LMNAPTGS2
SCHEMBL27950503 0.78 EDNRA (0.52) POLBCASP6CYP2C9ATMABCB1
SCHEMBL16397347 0.77 STK17B (0.43) POLBCASP6MAOBLMNA
SCHEMBL27219661 0.75 POLB (0.39) POLBCASP6CYP2C9ATMEDNRA
SCHEMBL7422948 0.75 KMT2A (0.41) POLBCASP6ABCB1MEN1USP2
SCHEMBL27950497 0.75 ABCB1 (0.44) CYP2C9ABCB1MEN1USP2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567225-A Method for preparing dicarboxylic acid compound from olefin 徐州医科大学 2024-02-20 CN disclosed
CN-117210834-A Electrochemical-based promotion of CO 2 Method for synthesizing dicarboxylic acid compound 四川大学 2023-12-12 CN disclosed