Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 11/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18741276 | 1.00 | FOLH1 (0.55) | FOLH1SLC6A5CPB2GSRRNPEP | |
| SCHEMBL13049083 | 0.88 | FOLH1 (0.57) | FOLH1SLC6A5CPB2GSRRNPEP | |
| SCHEMBL29187387 | 0.88 | FOLH1 (0.57) | FOLH1SLC6A5CPB2GSRRNPEP | |
| SCHEMBL29918590 | 0.87 | FOLH1 (0.55) | FOLH1SLC6A5CPB2GSRRNPEP | |
| SCHEMBL22689972 | 0.85 | FOLH1 (0.54) | FOLH1SLC6A5CPB2GSRCA1 | |
| SCHEMBL22689833 | 0.85 | FOLH1 (0.54) | FOLH1SLC6A5CPB2GSRRNPEP | |
| SCHEMBL7165076 | 0.83 | FOLH1 (0.50) | FOLH1SLC6A5CPB2GSRCA1 | |
| SCHEMBL7165072 | 0.83 | FOLH1 (0.50) | FOLH1SLC6A5CPB2GSRCA1 | |
| SCHEMBL7165075 | 0.83 | FOLH1 (0.50) | FOLH1SLC6A5CPB2GSRCA1 | |
| SCHEMBL1710876 | 0.83 | FOLH1 (0.51) | FOLH1SLC6A5CPB2GSRRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12510549-B2 | Reagents and methods for detecting protein lysine 2-hydroxyisobutyrylation | PTM BIOLAB INC. (CN) | 2025-12-30 | — | — | US | disclosed |
| US-20220091134-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN LYSINE 2-HYDROXYISOBUTYRYLATION | PTM BIOLAB INC. (CN) | 2022-03-24 | — | — | US | disclosed |
| US-11204353-B2 | Reagents and methods for detecting protein lysine 2-hydroxyisobutyrylation | PTM BIOLAB INC. (CN) | 2021-12-21 | — | — | US | disclosed |
| US-20190145986-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN LYSINE 2-HYDROXYISOBUTYRYLATION | PTM BIO LLC (US) | 2019-05-16 | — | — | US | disclosed |
| WO-2017064718-A1 | METHODS AND KITS FOR DETERMINING DEACYLASE ACTIVITY | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2017-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12510549-B2 | Reagents and methods for detecting protein lysine 2-hydroxyisobutyrylation | STUB1, DEK, PHKB | FOLH1 3128/4885SLC6A5 3916/4885CPB2 2839/4885 |
| US-20190145986-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN LYSINE 2-HYDROXYISOBUTYRYLATION | STUB1, ABHD14B, PTMS | FOLH1 1166/4885SLC6A5 3566/4885CPB2 50/4885 |
| US-11204353-B2 | Reagents and methods for detecting protein lysine 2-hydroxyisobutyrylation | STUB1, ABHD14B, PTMS | FOLH1 1166/4885SLC6A5 3566/4885CPB2 50/4885 |
| US-20220091134-A1 | REAGENTS AND METHODS FOR DETECTING PROTEIN LYSINE 2-HYDROXYISOBUTYRYLATION | STUB1, ABHD14B, PTMS | FOLH1 1166/4885SLC6A5 3566/4885CPB2 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.