Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23374534 | 0.84 | DRD2 (0.65) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL23374714 | 0.84 | DRD2 (0.65) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL18745412 | 0.83 | CYP11B2 (0.56) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL16410879 | 0.83 | DRD2 (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL17779211 | 0.80 | DRD2 (0.72) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8389997 | 0.79 | DRD2 (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL17774400 | 0.79 | DRD2 (0.47) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL20611963 | 0.76 | LSS (0.50) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL23374659 | 0.74 | SLC18A3 (0.56) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12447397 | 0.74 | SLC18A3 (0.56) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624211-B2 | Anti-cancer compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-04-18 | — | — | US | disclosed |