Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | EIF4E | P06730 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15788463 | 0.88 | PNP (0.73) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL13606969 | 0.83 | PNP (0.69) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL4967368 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL18735565 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL3307695 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL2631656 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL12758161 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL16330745 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL6981526 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA | |
| Taribavirin SCHEMBL3307685 | 0.83 | PNP (1.00) | PNPLMNASMN1; SMN2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624249-B2 | Nucleoside kinase bypass compositions and methods | MERCK SHARP & DOHME CORP. (US) | 2017-04-18 | — | — | US | disclosed |