Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.44 |
| ▸ | TEK | Q02763 | 5/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ABL2 | P42684 | 2/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241440 | 0.85 | SRC (0.61) | SRCTEKLCKKDREGFR | |
| SCHEMBL18744617 | 0.83 | SRC (0.46) | SRCTEKLCKKDREGFR | |
| SCHEMBL18744658 | 0.81 | SRC (0.44) | SRCTEKLCKKDRCCNA2 | |
| SCHEMBL18744657 | 0.80 | SRC (0.45) | SRCTEKLCKKDRCDK2 | |
| SCHEMBL19277019 | 0.80 | DYRK3 (0.52) | SRCTEKLCKADK | |
| SCHEMBL13656694 | 0.80 | DYRK3 (0.52) | SRCTEKLCKADK | |
| SCHEMBL18744642 | 0.78 | PIKFYVE (0.49) | SRCTEKLCKKDREGFR | |
| SCHEMBL13656692 | 0.74 | ADK (0.48) | SRCLCKKDREGFRADK | |
| SCHEMBL18744602 | 0.74 | SRC (0.65) | SRCTEKLCKKDREGFR | |
| SCHEMBL13063927 | 0.73 | PRMT5 (0.39) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624257-B2 | 7-deazapurine nucleosides for therapeutic uses | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ASCR, V.V.I. (CZ) | 2017-04-18 | — | — | US | disclosed |