Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.45 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CSK | P41240 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | TEK | Q02763 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241440 | 0.86 | SRC (0.61) | SRCABL1EGFRTEKLCK | |
| SCHEMBL18744642 | 0.82 | PIKFYVE (0.49) | SRCABL1RIPK2EGFRTEK | |
| SCHEMBL18744658 | 0.80 | SRC (0.44) | SRCABL1CDK2EGFRTEK | |
| SCHEMBL18744587 | 0.80 | SRC (0.44) | SRCABL1CDK2EGFRTEK | |
| SCHEMBL13656694 | 0.79 | DYRK3 (0.52) | SRCPRKD3PRKD2CSNK1DTEK | |
| SCHEMBL19277019 | 0.79 | DYRK3 (0.52) | SRCPRKD3PRKD2CSNK1DTEK | |
| SCHEMBL18744617 | 0.79 | SRC (0.46) | SRCABL1EGFRTEKLCK | |
| SCHEMBL18744602 | 0.75 | SRC (0.65) | SRCABL1EGFRTEKLCK | |
| SCHEMBL13063927 | 0.75 | PRMT5 (0.39) | — | |
| SCHEMBL13656692 | 0.74 | ADK (0.48) | SRCEGFRLCKKDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624257-B2 | 7-deazapurine nucleosides for therapeutic uses | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ASCR, V.V.I. (CZ) | 2017-04-18 | — | — | US | disclosed |