Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 9/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.44 |
| ▸ | SMO | Q99835 | 4/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18745977 | 0.94 | MAOB (0.44) | MAOBMAPK10MAPK8SMOMAPK13 | |
| SCHEMBL1665724 | 0.90 | MAOB (0.47) | MAOBMAPK10MAPK8SMOMAPK13 | |
| SCHEMBL1664953 | 0.90 | MAOB (0.52) | MAOBMAPK10MAPK8SMOMAPK13 | |
| SCHEMBL1664674 | 0.88 | MAOB (0.52) | MAOBMAPK10MAPK8SMOMAPK13 | |
| SCHEMBL8773401 | 0.87 | MAOB (0.43) | MAOBMAPK10MAPK8SMOMAOA | |
| SCHEMBL1665611 | 0.86 | MAPT (0.47) | MAOBMAPK10MAPK8SMOMAOA | |
| SCHEMBL1664039 | 0.86 | HPGDS (0.46) | MAOBMAPK10MAPK8MAPK13MAPK12 | |
| SCHEMBL1664592 | 0.85 | MAOB (0.43) | MAOBMAPK10MAPK8SMOMAPK13 | |
| SCHEMBL1665764 | 0.83 | MAOB (0.41) | MAOBMAPK10MAPK8SMOMAPK13 | |
| SCHEMBL13964702 | 0.83 | MAOB (0.45) | MAOBMAPK10MAPK8SMOMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9622991-B2 | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARMACEUTICALS INC. (US) | 2017-04-18 | — | — | US | disclosed |