Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773394 | 0.94 | MAOB (0.43) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL1665724 | 0.89 | MAOB (0.47) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL1664953 | 0.88 | MAOB (0.52) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL18745985 | 0.87 | MAOB (0.45) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL1664674 | 0.86 | MAOB (0.52) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL1665611 | 0.85 | MAPT (0.47) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL1664039 | 0.83 | HPGDS (0.46) | MAOBMAOAACHEMAPK10MAPK8 | |
| SCHEMBL1664592 | 0.82 | MAOB (0.43) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL1665764 | 0.82 | MAOB (0.41) | MAOBMAOAACHESMOMAPK10 | |
| SCHEMBL18745977 | 0.81 | MAOB (0.44) | MAOBMAOAACHESMOMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295904-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | MPL, CSF3R, HGF | MAOB 4439/4885MAOA 4542/4885ACHE 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.