Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17244801 | 1.00 | ALDH1A1 (0.69) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL28248089 | 0.95 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Ethyl Oleate SCHEMBL27479328 | 0.95 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| Dectaflur SCHEMBL22689506 | 0.95 | ALDH1A1 (0.63) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL23595590 | 0.91 | ALOX15 (0.80) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL15442495 | 0.91 | ALOX15 (0.80) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL15445279 | 0.91 | ALOX15 (0.80) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL15457464 | 0.91 | ALOX15 (0.80) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL15442493 | 0.91 | ALOX15 (0.80) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1471510 | 0.89 | CYP1A2 (0.83) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575764-B1 | BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2017-04-19 | — | — | EP | disclosed |