Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859587 | 0.91 | NPC1 (0.44) | NPC1RAB9AKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10074197 | 0.89 | NPC1 (0.44) | NPC1RAB9AKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL7849187 | 0.89 | NPC1 (0.44) | NPC1RAB9AKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL31047967 | 0.83 | TNF (0.39) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7857212 | 0.83 | TNF (0.39) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18747986 | 0.81 | ALOX15 (0.36) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10192666 | 0.81 | NPC1 (0.43) | NPC1RAB9AKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2254579 | 0.81 | NPC1 (0.47) | NPC1RAB9AKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL15247750 | 0.79 | KDM4E (0.44) | KMT2ASMN1; SMN2MEN1MAPTALDH1A1 | |
| SCHEMBL6368923 | 0.79 | KDM4E (0.37) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107193-A1 | CRYSTALLINE LENALIDOMIDE PROCESS | SHILPA MEDICARE LIMITED (IN) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107193-A1 | CRYSTALLINE LENALIDOMIDE PROCESS | SF3B1, SF3B2, LAS1L | NPC1 3278/4885RAB9A 2936/4885KMT2A 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.