Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 9/20 | 0.52 |
| ▸ | MC5R | P33032 | 9/20 | 0.52 |
| ▸ | MC3R | P41968 | 9/20 | 0.52 |
| ▸ | MC1R | Q01726 | 9/20 | 0.52 |
| ▸ | CTSG | P08311 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | GRB7 | Q14451 | 1/20 | 0.48 |
| ▸ | TSLP | Q969D9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14962542 | 0.95 | MC4R (0.53) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL18507118 | 0.95 | MC4R (0.52) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL22808197 | 0.95 | MC4R (0.52) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL22382219 | 0.94 | MC4R (0.52) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL22382215 | 0.90 | TSLP (0.54) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL14107743 | 0.90 | TSLP (0.54) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL14107827 | 0.90 | TSLP (0.54) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL20809943 | 0.89 | GRB7 (0.54) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL12462669 | 0.89 | GRB7 (0.54) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL10046415 | 0.89 | GRB7 (0.54) | MC4RMC5RMC3RMC1RCTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467365-B1 | RADIOIODINATION METHOD | GE HEALTHCARE LTD (GB) | 2017-08-09 | — | — | EP | disclosed |
| EP-2509638-B1 | IODINE RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2017-04-19 | — | — | EP | disclosed |