Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.37 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18748936 | 0.93 | RAB9A (0.42) | RAB9ANPSR1MAPTNPC1MRGPRX4 | |
| SCHEMBL18514810 | 0.91 | RAB9A (0.39) | RAB9ANPSR1MAPTNPC1MRGPRX4 | |
| SCHEMBL18748988 | 0.91 | ALDH1A1 (0.45) | RAB9ANPSR1MAPTNPC1MRGPRX4 | |
| SCHEMBL18748836 | 0.90 | MAPT (0.48) | RAB9ANPSR1MAPTNPC1MRGPRX4 | |
| SCHEMBL18749012 | 0.90 | RAB9A (0.40) | RAB9ANPSR1MAPTNPC1KMT2A | |
| SCHEMBL18748860 | 0.90 | RAB9A (0.40) | RAB9ANPSR1MAPTNPC1KMT2A | |
| SCHEMBL18748847 | 0.90 | ALDH1A1 (0.43) | RAB9ANPC1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18749220 | 0.90 | RAB9A (0.42) | RAB9ANPSR1MAPTNPC1MRGPRX4 | |
| SCHEMBL18748796 | 0.89 | MRGPRX4 (0.47) | RAB9ANPSR1MAPTNPC1MRGPRX4 | |
| SCHEMBL18748938 | 0.88 | MAPT (0.44) | RAB9ANPSR1MAPTNPC1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040768-B2 | Carbamate compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-08-07 | — | — | US | disclosed |
| US-9907307-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20180014539-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-18 | — | — | US | disclosed |
| US-20180002291-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20180002294-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20170360044-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20170342032-A1 | CARBAMATE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-11-30 | — | — | US | disclosed |
| US-9788547-B2 | Aromatic compound and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-17 | — | — | US | disclosed |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040768-B2 | Carbamate compound and use thereof | C9, C5, C1S | RAB9A 759/4885NPSR1 2694/4885MAPT 3358/4885 |
| US-20180014539-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | RAB9A 758/4885NPSR1 2778/4885MAPT 3347/4885 |
| US-20170360044-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | RAB9A 676/4885NPSR1 2764/4885MAPT 3184/4885 |
| US-20170342032-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | RAB9A 684/4885NPSR1 2767/4885MAPT 3169/4885 |
| US-20180002291-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | RAB9A 649/4885NPSR1 2837/4885MAPT 3308/4885 |
| US-20170105413-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-0 | RAB9A 143/4885NPSR1 1960/4885MAPT 3329/4885 |
| US-20170105416-A1 | AROMATIC COMPOUND AND USES THEREOF | TYR, H1-3, H1-10 | RAB9A 338/4885NPSR1 2148/4885MAPT 2998/4885 |
| US-20180002294-A1 | CARBAMATE COMPOUND AND USE THEREOF | C9, C5, C1S | RAB9A 759/4885NPSR1 2694/4885MAPT 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.