SCHEMBL18750482

SCHEMBL18750482

[N-]=[N+]=NCCOCCOCCOCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.32
▸ MGMT P16455 1/20 0.32
▸ ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21090258 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL30180781 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL21090765 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL25345611 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL25495530 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL24629752 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL25495560 0.98 CRBN (0.30) CRBN
SCHEMBL25976305 0.96 CRBN (0.31) CRBN
SCHEMBL25496794 0.95 TTR (0.33) CRBN
SCHEMBL24894500 0.93 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170107289-A1 INTRACELLULAR DELIVERY COMPOUNDS SORRENTO THERAPEUTICS, INC. 2017-04-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107289-A1 INTRACELLULAR DELIVERY COMPOUNDS NPC1L1, CHERP, CHMP4B CRBN 3074/4885MGMT 4621/4885ABCG2 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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