SCHEMBL21090765

SCHEMBL21090765

[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.32
▸ MGMT P16455 1/20 0.32
▸ ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18750482 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL21090258 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL30180781 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL25345611 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL25495530 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL24629752 1.00 CRBN (0.32) CRBNMGMTABCG2
SCHEMBL25495560 0.98 CRBN (0.30) CRBN
SCHEMBL25976305 0.96 CRBN (0.31) CRBN
SCHEMBL25496794 0.95 TTR (0.33) CRBN
SCHEMBL24894500 0.93 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551230-A2 MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY Dyne Therapeutics, Inc. (US) 2025-05-14 — — EP disclosed
CN-119630407-A Muscle targeting complexes and their use for the treatment of facial shoulder humerus muscular dystrophy 达因疗法公司 2025-03-14 — — CN disclosed
WO-2024011135-A2 MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY DYNE THERAPEUTICS, INC. (US) 2024-01-11 — — WO disclosed
EP-4271478-A1 MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY Dyne Therapeutics, Inc. (US) 2023-11-08 — — EP disclosed
CN-116916938-A Muscle targeting complexes and their use for the treatment of facial shoulder humerus muscular dystrophy 达因疗法公司 2023-10-20 — — CN disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed
US-20230044430-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES KRANTZ ALEXANDER (US) 2023-02-09 — — US disclosed
EP-4087584-A2 CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2022-11-16 — — EP disclosed
CN-115315263-A Cell surface receptor binding compounds and conjugates 利西亚治疗公司 2022-11-08 — — CN disclosed
US-11400165-B2 Composition and method for modifying polypeptides ADVANCED PROTEOME THERAPEUTICS INC. (US) 2022-08-02 — — US disclosed
WO-2022147207-A1 MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY DYNE THERAPEUTICS, INC. (US) 2022-07-07 — — WO disclosed
US-20220096649-A1 IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE HORIZON TECHNOLOGY FINANCE CORPORATION 2022-03-31 — — US disclosed
US-20190175750-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES ADVANCED PROTEOME THERAPEUTICS INC. 2019-06-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230044430-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES PTMS, SRMS, ACP1 CRBN 7/4885MGMT 2883/4885ABCG2 1401/4885
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R CRBN 3454/4885MGMT 2296/4885ABCG2 675/4885
US-11400165-B2 Composition and method for modifying polypeptides PTMS, SRMS, ACP1 CRBN 7/4885MGMT 2883/4885ABCG2 1401/4885
US-20190175750-A1 COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES PTMS, SRMS, ACP1 CRBN 7/4885MGMT 2883/4885ABCG2 1401/4885
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A CRBN 2889/4885MGMT 4124/4885ABCG2 337/4885
US-20220096649-A1 IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE PBK, CD47, NCL CRBN 1518/4885MGMT 2581/4885ABCG2 2782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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