Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940662 | 0.92 | AURKA (0.36) | PIM1TTKPIM2 | |
| SCHEMBL9941211 | 0.88 | PIM1 (0.36) | PIM1TTKPIM2 | |
| SCHEMBL9941368 | 0.86 | SCN9A (0.40) | PIM1TTKPIM2 | |
| SCHEMBL9942368 | 0.84 | PIM1 (0.35) | PIM1TTKPIM2 | |
| SCHEMBL18752120 | 0.84 | PIM1 (0.35) | PIM1TTKPIM2 | |
| SCHEMBL10219356 | 0.83 | PLK1 (0.41) | — | |
| SCHEMBL9940571 | 0.80 | CCNA2 (0.41) | — | |
| SCHEMBL9940675 | 0.79 | PIM1 (0.43) | PIM1TTKPIM2 | |
| SCHEMBL9940573 | 0.76 | PLK1 (0.41) | PIM1TTKPIM2 | |
| SCHEMBL9940756 | 0.76 | AURKA (0.38) | PIM1TTKPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614065-B1 | SUBSTITUTED PYRAZOLO-QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2017-04-19 | — | — | EP | disclosed |