Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19510002 | 1.00 | DPP4 (0.47) | DPP4DPP7DPP8 | |
| SCHEMBL1644943 | 0.86 | DPP4 (0.51) | DPP4DPP7DPP8 | |
| SCHEMBL3985105 | 0.86 | DPP4 (0.51) | DPP4DPP7DPP8 | |
| SCHEMBL3992304 | 0.86 | DPP4 (0.51) | DPP4DPP7DPP8 | |
| SCHEMBL25663565 | 0.86 | DPP4 (0.51) | DPP4DPP7DPP8 | |
| SCHEMBL28177515 | 0.83 | DPP4 (0.41) | DPP4DPP7DPP8 | |
| SCHEMBL28261299 | 0.81 | DPP4 (0.47) | DPP4DPP7DPP8 | |
| SCHEMBL743042 | 0.80 | DPP4 (0.53) | DPP4DPP7DPP8 | |
| SCHEMBL571909 | 0.80 | DPP4 (0.53) | DPP4DPP7DPP8 | |
| SCHEMBL29619671 | 0.80 | DPP4 (0.53) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305822-A1 | METHOD FOR PREPARING SITAGLIPTIN INTERMEDIATE VIA ASYMMETRICAL REDUCTION METHOD | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2017-10-26 | — | — | US | disclosed |
| EP-3156391-A1 | METHOD FOR PREPARING SITAGLIPTIN INTERMEDIATE VIA ASYMMETRICAL REDUCTION METHOD | Zhejiang Huahai Pharmaceutical Co., Ltd (CN) | 2017-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305822-A1 | METHOD FOR PREPARING SITAGLIPTIN INTERMEDIATE VIA ASYMMETRICAL REDUCTION METHOD | DPP4, DPP7, SI | DPP4 1/4885DPP7 2/4885DPP8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.