Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16115480 | 0.88 | KCNA5 (0.40) | KCNA5ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL16137776 | 0.86 | MAPT (0.41) | KCNA5ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL7112200 | 0.85 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL31477291 | 0.85 | ALDH1A1 (0.43) | KCNA5ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL31477670 | 0.84 | ALDH1A1 (0.42) | KCNA5ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL17798382 | 0.84 | ALDH1A1 (0.42) | KCNA5ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL6925400 | 0.82 | ALDH1A1 (0.44) | KCNA5ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL8770921 | 0.82 | KCNA5 (0.50) | KCNA5L3MBTL1 | |
| SCHEMBL2029513 | 0.81 | ALDH1A1 (0.41) | KCNA5ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL14445159 | 0.81 | KMT2A (0.42) | KCNA5ALDH1A1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |