Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31477291 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| SCHEMBL15270484 | 0.88 | MMP8 (0.44) | ALDH1A1MAPTPOLBKDM4EGAA | |
| SCHEMBL17798382 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| SCHEMBL31477670 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| SCHEMBL6925400 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL18754138 | 0.85 | KCNA5 (0.48) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| SCHEMBL2029513 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| SCHEMBL14445159 | 0.84 | KMT2A (0.42) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| Propionic Acid SCHEMBL31477215 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBKDM4EMAPK1 | |
| SCHEMBL2847713 | 0.83 | LMNA (0.46) | MAPTKDM4EGAALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |