Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.53 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.53 |
| ▸ | YAP1 | P46937 | 1/20 | 0.53 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13592382 | 0.87 | MAPT (0.68) | CARM1PRMT6MAPTMEN1KMT2A | |
| SCHEMBL10306602 | 0.81 | MAPT (0.58) | CARM1PRMT6MAPTMEN1KMT2A | |
| SCHEMBL14144775 | 0.80 | CTNNB1 (0.64) | CTNNB1TCF7L2 | |
| SCHEMBL13947459 | 0.79 | CTNNB1 (0.82) | CTNNB1TCF7L2 | |
| SCHEMBL20069165 | 0.78 | PKM (0.74) | CARM1PRMT6MAPTMEN1KMT2A | |
| SCHEMBL10212156 | 0.78 | PKM (0.74) | CARM1PRMT6MAPTMEN1KMT2A | |
| SCHEMBL23928217 | 0.78 | POLB (0.55) | CARM1PRMT6MAPTMEN1KMT2A | |
| SCHEMBL23928125 | 0.78 | POLB (0.52) | CARM1PRMT6MAPTMEN1KMT2A | |
| SCHEMBL13746186 | 0.77 | NPSR1 (0.72) | MAPTTDP1 | |
| SCHEMBL10306612 | 0.77 | POLB (0.74) | MAPTMEN1KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651913-B1 | INDENO-FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES | TRANSITIONS OPTICAL INC (US) | 2017-04-19 | — | — | EP | disclosed |