Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962777 | 0.94 | MAPT (0.42) | P2RX1NPC1RAB9AMAPTLMNA | |
| SCHEMBL18754293 | 0.88 | P2RX1 (0.49) | P2RX1KCNK3NPC1RAB9AMAPT | |
| SCHEMBL1960938 | 0.82 | MEN1 (0.44) | P2RX1NPC1RAB9AMAPTLMNA | |
| SCHEMBL29664191 | 0.80 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL15807047 | 0.80 | NQO2 (0.36) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL6113940 | 0.76 | PTGS2 (0.31) | — | |
| SCHEMBL16713281 | 0.75 | SLC6A2 (0.44) | MAPTPOLBGAA | |
| SCHEMBL1958041 | 0.73 | LMNA (0.33) | MAPTLMNANPSR1 | |
| SCHEMBL16742523 | 0.72 | PDK2 (0.41) | — | |
| SCHEMBL2014165 | 0.71 | AKR1C3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651913-B1 | INDENO-FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES | TRANSITIONS OPTICAL INC (US) | 2017-04-19 | — | — | EP | disclosed |