Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 4/20 | 0.35 |
| ▸ | BIRC3 | Q13489 | 4/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | TSG101 | Q99816 | 4/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747486 | 0.84 | PRMT5 (0.46) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL10060515 | 0.84 | PRMT5 (0.46) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL14262326 | 0.83 | PRMT5 (0.46) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL13164737 | 0.82 | PRMT5 (0.42) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL11952927 | 0.79 | PRMT5 (0.44) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL10060330 | 0.79 | PRMT5 (0.44) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL13203414 | 0.77 | PRMT5 (0.46) | PRMT5WDR77TSG101NAALAD2MAP1LC3B | |
| SCHEMBL12651696 | 0.75 | TSG101 (0.38) | XIAPBIRC3BIRC2PRMT5WDR77 | |
| SCHEMBL10060329 | 0.74 | BIRC2 (0.48) | XIAPBIRC3BIRC2 | |
| SCHEMBL13034324 | 0.73 | BIRC2 (0.49) | XIAPBIRC3BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534170-B1 | IAP BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC (CA) | 2017-04-19 | — | — | EP | disclosed |