SCHEMBL18756255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6709616	0.83	CA12 (0.44)	APLNRCA12CA14CA2CA1
	SCHEMBL7403514	0.82	MEN1 (0.45)	APLNRCA12CA14CA2CA1
	SCHEMBL14015716	0.82	MEN1 (0.45)	APLNRCA12CA14CA2CA1
	SCHEMBL14155384	0.82	MEN1 (0.45)	APLNRCA12CA14CA2CA1
	SCHEMBL6709591	0.80	CA1 (0.46)	APLNRCA12CA14CA2CA1
	SCHEMBL2671597	0.78	APLNR (0.46)	APLNRCA12CA14CA2CA1
	SCHEMBL2197146	0.77	APLNR (0.42)	APLNRCA2CA1CA7CYP2D6
	SCHEMBL5325084	0.77	APLNR (0.42)	APLNRCA12CA14CA2CA1
	SCHEMBL2194505	0.77	APLNR (0.42)	APLNRCA2CA1CA7CYP2D6
	SCHEMBL19091350	0.77	APLNR (0.42)	APLNRCA2CA1CA7CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.