SCHEMBL18756282

SCHEMBL18756282

C=C(O)C(C)(C)NCC(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21322186 0.76 CYP2D6 (0.46) CYP2D6CYP2C19
SCHEMBL25769641 0.73 CYP2D6 (0.42) CYP2D6CYP2C19
SCHEMBL8258124 0.72
SCHEMBL2847967 0.70 CYP2D6 (0.39) CYP2D6CYP2C19
SCHEMBL3698430 0.69
SCHEMBL19216088 0.68
SCHEMBL270919 0.68
SCHEMBL7117040 0.65 PKM (0.33) CYP2D6CYP2C19
SCHEMBL19228201 0.65 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL15359354 0.64 CYP2D6 (0.34) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3156410-A1 POLYENE MACROLIDE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2017-04-19 EP disclosed