Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24843107 | 0.78 | ADH1B (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL25955452 | 0.74 | — | — | |
| SCHEMBL21025625 | 0.72 | — | — | |
| SCHEMBL270919 | 0.71 | — | — | |
| SCHEMBL2014765 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL7117040 | 0.68 | PKM (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL16689785 | 0.67 | — | — | |
| SCHEMBL3156858 | 0.67 | PIK3CD (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL3698430 | 0.67 | — | — | |
| SCHEMBL20115351 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755958-B9 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS MODULATORS OF KINASE ACTIVITY | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-2755958-B1 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS MODULATORS OF KINASE ACTIVITY | MERCK PATENT GMBH (DE) | 2017-08-09 | — | — | EP | disclosed |