Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091348 | 0.78 | DGAT1 (0.38) | DGAT1MEN1KMT2AMAOB | |
| SCHEMBL20883232 | 0.72 | GRM4 (0.32) | MEN1KMT2A | |
| SCHEMBL11769509 | 0.72 | GRM4 (0.32) | MEN1KMT2A | |
| SCHEMBL2824169 | 0.71 | — | — | |
| SCHEMBL21380367 | 0.67 | DGAT1 (0.43) | DGAT1MAOB | |
| SCHEMBL20166942 | 0.67 | — | — | |
| SCHEMBL3903447 | 0.65 | DGAT1 (0.41) | DGAT1MAOB | |
| SCHEMBL1552389 | 0.64 | MEN1 (0.63) | MEN1KMT2A | |
| SCHEMBL11351843 | 0.62 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL24038945 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |