SCHEMBL1552389

SCHEMBL1552389

NNC(=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
HTT P42858 3/20 0.57
ALDH1A1 P00352 3/20 0.57
CRHBP P24387 1/20 0.57
CRHR2 Q13324 1/20 0.57
MCOLN3 Q8TDD5 1/20 0.57
GLA P06280 1/20 0.52
KDM4E B2RXH2 1/20 0.50
LMNA P02545 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
P2RX7 Q99572 1/20 0.46
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
ITGB1 P05556 1/20 0.44
ITGA4 P13612 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24038945 0.90
SCHEMBL26928719 0.86 ALDH1A1 (0.55) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL16684401 0.82 MEN1 (0.47) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL5105057 0.80 ALDH1A1 (0.50) MEN1KMT2AALDH1A1KDM4EP2RX7
SCHEMBL5092050 0.78 ALDH1A1 (0.49) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL14382347 0.78 ALDH1A1 (0.49) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL31053476 0.78 HTT (0.53) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL28289553 0.78 ALDH1A1 (0.53) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL5528066 0.77 ALDH1A1 (0.42) MEN1KMT2AHTTALDH1A1CRHBP
SCHEMBL2841738 0.76 THRB (0.63) MEN1KMT2AHTTALDH1A1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996016982-A2 ULTRASELECTIVE OPIOIDMIMETIC PEPTIDES AND PHARMACOLOGICAL AND THERAPEUTIC USES THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-06-06 WO claimed
CN-1040191-A Parasiticidal N '-replacement-N-alkyl-carbonyl-N '-acylhydrazine and N '-replacement-N-acyl group-N '-alkyl-carbonyl hydrazine ROHM & HAAS (US) 1990-03-07 CN claimed
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
CN-119822990-A Adamantane isopropanolamine structure compound and preparation method and application thereof 贵州大学 2025-04-15 CN disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20230322976-A1 METHOD OF EVALUATING DEGREE OF PURITY OF PHARMACEUTICAL SUBSTANCE CONTAINED IN COMPOSITE BODY, AND METHOD OF PRODUCING COMPOSITE BODY BIODYNAMIC RESEARCH FOUNDATION (JP) 2023-10-12 US disclosed
CN-113999222-B Adamantyl oxadiazole-containing compound and preparation method and application thereof 贵州大学 2023-06-27 CN disclosed
EP-4190824-A1 METHOD FOR EVALUATING DEGREE OF PURITY OF PHARMACEUTICAL SUBSTANCE CONTAINED IN COMPOSITE BODY, AND METHOD FOR PRODUCING COMPOSITE BODY Toray Industries, Inc. (JP) 2023-06-07 EP disclosed
WO-2003075660-A1 METHOD OF TREATMENT OR PREVENTION OF OBESITY MERCK & CO., INC. (US) 2003-09-18 WO disclosed
WO-2003065983-A2 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 INHIBITORS USEFUL FOR THE TREATMENT OF DIABETES, OBESITY AND DYSLIPIDEMIA MERCK & CO., INC. (US) 2003-08-14 WO disclosed
EP-0934283-A2 ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-08-11 EP disclosed
US-5780589-A DIPEPTIDES, TRIPEPTIDES OR CYCLIC PEPTIDES AS ANTAGONIST OF OPIOID RECEPTORS TREATING DRUG ABUSE, DRUG DEPENDENCE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-07-14 US disclosed
WO-1998005652-A2 ARTHROPODICIDAL AND FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-12 WO disclosed
WO-1996016982-A2 ULTRASELECTIVE OPIOIDMIMETIC PEPTIDES AND PHARMACOLOGICAL AND THERAPEUTIC USES THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-06-06 WO disclosed
WO-1993000359-A1 MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-01-07 WO disclosed
US-4097599-A PESTICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1978-06-27 US disclosed
US-4038405-A MITICIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885HTT 2860/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885HTT 2860/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885HTT 2860/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885HTT 2860/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885HTT 2860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.