Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18758332 | 0.78 | BCHE (0.34) | BCHEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23701914 | 0.77 | BCHE (0.33) | BCHEGRM2 | |
| SCHEMBL25362255 | 0.72 | GRM2 (0.32) | GRM2 | |
| SCHEMBL18758329 | 0.71 | LOXL2 (0.31) | — | |
| SCHEMBL25364182 | 0.71 | GRM2 (0.38) | MEN1KMT2AGRM2 | |
| SCHEMBL25363478 | 0.69 | HDAC1 (0.35) | SMN1; SMN2GRM2 | |
| SCHEMBL18758335 | 0.69 | LOXL2 (0.39) | — | |
| SCHEMBL28370917 | 0.68 | GCK (0.33) | BCHE | |
| SCHEMBL20536551 | 0.66 | HDAC1 (0.31) | BCHE | |
| SCHEMBL23353906 | 0.64 | MMP13 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066606-A1 | EPOTHILONE ANALOGS, METHODS OF SYNTHESIS, METHODS OF TREATMENT, AND DRUG CONJUGATES THEREOF | WILLIAM MARSH RICE UNIVERSITY (US) | 2017-04-20 | — | — | WO | disclosed |